Curia étend ses capacités dans le domaine des produits biologiques en accédant à l’ADN doggybone de Touchlight

Curia collabore avec Touchlight afin d’élargir son offre de fabrication d’ARNm pour permettre l’accès à l’ADN enzymatique doggybone (dbDNA™)

ALBANY, New York, et Hampton, Royaume-Uni, 25 juill. 2023 (GLOBE NEWSWIRE) — Curia, une organisation de premier plan dans le domaine de la recherche, du développement et de la fabrication en sous-traitance, et Touchlight, une société pionnière dans la production enzymatique d’ADN, ont annoncé aujourd’hui un accord qui fournira à Curia ainsi qu’à ses clients un moyen simplifié d’accès à l’ADN doggybone de Touchlight (dbDNA). L’arrangement étend les offres de fabrication d’ARNm de Curia avec une source supplémentaire et différenciée de matière première d’ADN qui est immédiatement accessible par les clients de Curia. Dans le cadre de l’accord, Touchlight fabriquera directement dbDNA pour le compte des clients de Curia.

« Curia reste déterminée à renforcer ses offres de produits biologiques et ses capacités de fabrication d’ARNm de bout en bout », a déclaré Christopher Conway, président de la R&D chez Curia. « Avec l’ajout de l’ADN enzymatique grâce à notre partenariat avec Touchlight, nos clients bénéficieront d’un avantage décisif en termes d’évolutivité et de rapidité de commercialisation. »

dbDNA de Touchlight est un vecteur d’ADN linéaire, à double brin, fermé de manière covalente. L’ADN sert de modèle pour l’élaboration des traitements à base d’ARNm. Grâce à un processus enzymatique simple appelé transcription in vitro, les informations génétiques sont copiées de l’ADN à l’ARNm. Cet ARNm est alors capable d’apprendre aux cellules à fabriquer des protéines spécifiques qui sont utilisées pour soigner ou prévenir des maladies. L’ADN enzymatique de Touchlight est produit par un processus enzymatique acellulaire qui offre des avantages inégalés en termes de rapidité, de qualité et de capacité par rapport à la production traditionnelle d’ADN plasmidique.

Karen Fallen, PDG de Touchlight, a commenté : « Nous sommes ravis de travailler avec Curia afin d’élargir l’accès à dbDNA en tant que matière de départ essentielle. Travailler en parallèle avec d’autres CDMO est un élément clé de notre volonté de permettre un large accès du marché à dbDNA. Curia met en place une solution complète pour l’ARNm, et cet accord permet aux deux entreprises d’étendre leur offre à un public plus large. »

dbDNA de Touchlight est une solution nouvelle, largement applicable et polyvalente, qui permet à Curia de renforcer ses capacités de fabrication d’ARNm en complément de son offre de plasmides de qualité bioprocédurale.

À propos de Curia

Curia est une une organisation de recherche, développement et fabrication en sous-traitance de premier plan qui fournit des produits et services allant de la R&D aux clients pharmaceutiques et biopharmaceutiques en passant par la fabrication commerciale. Basés sur 29 sites à travers les États-Unis, l’Europe et l’Asie, les près de 4 000 employés de Curia aident les clients de l’entreprise à passer de la curiosité à la guérison. Pour en savoir plus, rendez-vous sur CuriaGlobal.com.

À propos de Touchlight

Touchlight est une CDMO privée basée à Londres, au Royaume-Uni, qui se concentre sur la prestation de services d’ADN et la fabrication d’ADN doggybone (dbDNA™) produit de manière enzymatique pour permettre le développement de médicaments génétiques. Touchlight assure le développement et la fabrication rapides et enzymatiques d’ADN pour la production de tous les traitements avancés, comprenant l’ARNm, la thérapie génique virale et non virale, et l’API d’ADN. dbDNA est une structure minimale, linéaire et fermée de façon covalente, qui élimine les séquences bactériennes. La plateforme révolutionnaire de production enzymatique de Touchlight permet une vitesse et une échelle sans précédent, et offre la possibilité de cibler des gènes d’une taille et d’une complexité impossibles à atteindre avec les technologies actuelles. Les clients peuvent bénéficier d’une assistance depuis la phase préclinique jusqu’à l’octroi de licence et au transfert de technologie pour une utilisation en interne, en passant par le développement et l’approvisionnement.

Contact chez Curia :
Viana Bhagan
+1 518 512 2111
corporatecommunications@CuriaGlobal.com

Contact chez Touchlight :

Karen Fallen, présidente-directrice générale
Robin Bodicoat, directeur du marketing
E : info@touchlight.com
T : +44 20 8481 9200

GlobeNewswire Distribution ID 8880042

Curia expande sua capacidade biológica com acesso ao DNA doggybone da Touchlight

Curia colabora com a Touchlight para expandir sua oferta de produção de mRNA para permitir o acesso ao DNA enzimático de doggybone (dbDNA™)

ALBANY, N.Y. e HAMPTON, Reino Unido, July 25, 2023 (GLOBE NEWSWIRE) — A Curia, uma organização líder em contratação de pesquisa, desenvolvimento e fabricação, e a Touchlight, uma empresa pioneira na produção de DNA enzimático, anunciou hoje um acordo de fornecimento para a Curia e seus clientes de um acesso arrojado ao DNA doggybone (dbDNA) da Touchlight. O acordo expande as ofertas de produção de mRNA da Curia com uma fonte adicional diferenciada de matéria-prima de DNA imediatamente disponível para ser acessada pelos clientes da Curia. Sob o acordo, a Touchlight passará a produzir o dbDNA diretamente em nome dos clientes da Curia.

“A Curia continua empenhada a aprimorar nossas ofertas biológicas e capacidade de manufatura completa de mRNA”, disse Christopher Conway, presidente de P&D da Curia. “Com a adição do DNA enzimático por meio da nossa parceria com a Touchlight, nossos clientes terão uma vantagem essencial em termos de escalabilidade e velocidade no mercado.”

O dbDNA da Touchlight é um vetor de DNA linear, de fita dupla e fechado covalentemente. O DNA serve como modelo para terapias de mRNA. Através de um processo enzimático simples chamado transcrição in vitro, a informação genética é copiada do DNA para o mRNA. Este mRNA é então capaz de ensinar as células a produzir proteínas precisas que são usadas para tratar ou prevenir doenças. O DNA enzimático da Touchlight é produzido com um processo enzimático livre de células que oferece benefícios incomparáveis em velocidade, qualidade e capacidade quando comparado à produção tradicional de DNA de plasmídeo.

Karen Fallen, CEO da Touchlight, comentou: “É um grande prazer trabalhar com a Curia na maior expansão do acesso ao dbDNA como um material inicial essencial. O trabalho junto aos outros CDMOs é um componente essencial do nosso foco em permitir amplo acesso ao mercado de dbDNA. A Curia está criando uma solução abrangente de mRNA, e esse acordo permite que ambas as empresas ampliem sua oferta para um público mais amplo.”

O dbDNA da Touchlight é uma nova solução amplamente aplicável e versátil, avançando a capacidade de produção de mRNA da Curia como um complemento à sua oferta de plasmídeo de grau de bioprocessamento.

Sobre a Curia

A Curia é uma organização líder em contratos de pesquisa, desenvolvimento e fabricação que fornece produtos e serviços de P&D por meio da fabricação comercial para clientes farmacêuticos e biofarmacêuticos. Os quase 4.000 funcionários da Curia em 29 locais nos EUA, Europa e Ásia ajudam seus clientes a avançar da curiosidade para a cura. Saiba mais em CuriaGlobal.com.

Sobre a Touchlight

A Touchlight é uma CDMO de propriedade privada com sede em Londres, Reino Unido, focada no fornecimento de serviços de DNA e na fabricação de produtos enzimáticos doggybone DNA (dbDNA™) para permitir o desenvolvimento de medicamentos genéticos. A Touchlight fornece desenvolvimento e fabricação rápidos e enzimáticos de DNA para toda a produção de terapia avançada, incluindo mRNA, terapia gênica viral e não viral e API de DNA. O dbDNA é uma estrutura mínima, linear e covalentemente fechada, que elimina sequências bacterianas. A revolucionária plataforma de produção enzimática da Touchlight permite velocidade, escala e capacidade sem precedentes para o direcionamento de genes com um tamanho e complexidade impossíveis com as tecnologias atuais. Os clientes podem ser apoiados durante a fase pré-clínica, desenvolvimento e fornecimento, até o licenciamento e transferência de tecnologia para uso interno.

Contato da Curia:
Viana Bhagan
+1 518 512 2111
corporatecommunications@CuriaGlobal.com

Contato da Touchlight:

Karen Fallen, Diretora Executiva
Robin Bodicoat, Diretor de Marketing
E: info@touchlight.com
T: +44 (20) 8481 9200

GlobeNewswire Distribution ID 8880042

Speaker of Parliament commended for supporting sports development

The Upper West Regional Football Association (UWRFA) has commended Mr Alban S. K. Bagbin, the Speaker of Parliament, for his vested interest and contribution to the development of sports in the region.

As part of his contribution, Mr Bagbin had renovated the stands at the Wa Sports Stadium and was also sponsoring the Real Crusaders, a female football team, as well as donated sporting materials, including football jerseys to some other football clubs in the region.

The Speaker was also spearheading the construction of an ultra-modern astroturf in Nadowli in the Nadowli-Kaleo District, the home district of Mr Bagbin.

‘Look, as compared to other places, with this astroturf (in Nadowli) they can be playing matches 24 hours because there are going to be floor lights there.

So, when this astroturf is completed, I tell you it will help football to develop, especially in this (the Nadowli) catchment area,’ Alhaji Dauda Yahaya Sadugu, the Chairman of the UWRFA, said.

He gave the commendation in an interview with the Ghana News Agency, on the sidelines of an awards ceremony organised by TF Exponential FC, a Division Two football club in Nadowli.

He said the intervention by Mr Bagbin had a great impact on football development in the region and had saved the region from playing its Division One league home matches in other regions.

Mr Sadugu indicated that the Wa Sports Stadium was the only Football Association (FA) standard pitch for those matches but was in a dilapidated state until the intervention by the Speaker of Parliament.

He said the ongoing construction of an Astro turf in Tumu in the Sissala East Municipality and the Youth Resource Centre in Wa were expected to augment the number of FA standard pitches in the region to host Division One Matches when completed.

‘Second divisions are playing on selected pitches because the pitches are not good and now that we have a very good pitch (in Nadowli) yet to be completed it’s very remarkable,’ Mr Sadugu intimated.

The RFA Chairman said Home Marches of the Exponential FC and other clubs in the Nadowli-Kaleo District would be played within the district, when the construction of the astroturf in Nadowli was completed.

Mr Sadugu urged well-meaning citizens of the Upper West Region and beyond to support the development of football in the region through any means, including constructing befitting pitches across the districts, to help develop the football talents from the hinterlands.

He said due to the lack of standard pitches in the region some matches were currently played in the Jahan College of Education and the Wa Senior High School parks among others though they did not meet the FA standard of being fenced.

Source: Ghana News Agency

Paediatric Society of Ghana launches Child Road Safety Campaign

The Paediatric Society of Ghana (PSG) has launched a child road safety campaign to help save children from the dangers of using the roads.

The Child Road Safety campaign 2023 would involve Paediatricians and other health workers in collaborative efforts to end the increasing number of child victims of road crashes.

The Society is collaborating with the National Road Safety Authority (NSRA) and other key stakeholders to undertake extensive sensitisation on the worrying subject.

Dr. Hilda Boye, the President of Paediatric Society of Ghana, in her welcome address, mentioned that according to the WHO, a child died every four minutes from road traffic accidents, and enjoined all to take part actively in the campaign.

Dr. Kokou Amegan-Aho, a Consultant Paediatrician Haematologist, who is the head of the Department of Paediatrics and Child health, UHAS School of Medicine (SOM) launched the campaign, and said stakeholders needed to be concerned over the present fate of children using the nation’s roads.

He expressed the hope that the campaign would help to collate ideas to address the issue, adding that attention must be paid to the state of the nation’s roads.

‘There is a lot to do, and this campaign has come at the right time. It should bring innovative ways to prevent the trend of losing our children early to crashes’.

Mr. Bismark Elorm Sakitey, Assistant Planning Manager of the NSRA in the Volta Region, said in a report, that as of June, the national percentage of child fatalities in road crashes stood at 12.6 per cent compared to 22 per cent in the Volta Region.

He said human factors, including disregard for road rules by both drivers and pedestrians, account for the majority, adding that children remained among the most vulnerable groups.

The Assistant Planning Manager said parents should ensure the safety of their children in and out of school and called for effective collaboration with school management.

He advised children not to be sent out onto highways on errands and said child restraint for infants should be highly considered.

Madam Joan Fafa Ayer, Director for the road safety authority in the Volta and Oti Regions, said road crashes had a huge toll on the nation’s emergency services, and that the support of the medical fraternity was most welcome to drive interest in the campaign.

‘Having our doctors on board as advocates will help everyone know that it is the responsibility of all of us to; we all have a role to play,’ she said, and urged all to become advocates on road safety and join the campaign to end the carnage.

Dr. Emmanuel Oppong, Vice President of the Paediatric Society Ghana, commended the NSRA for the commitment and hoped all would join forces to ensure the safety of children using the roads.

Dr Richard Bright Danyoh, Acting Head of Paediatric and Child Health Sub BMC, Ho Teaching Hospital and chairman of the campaign, said a public engagement programme was being drawn for the campaign, including a stakeholder forum.

He detailed school visits, OPD and ward talks, the use of digital media, and open campaigns at markets and lorry parks as some of the modules for the programme.

There would also be durbars with traditional authorities and visits to religious houses.

Dr. Danyoh said medical professionals were considered role models and hoped their interest would encourage others, particularly children, to maintain safety on the roads.

The Society has also instituted a 1000-word essay competition on child road safety as part of the programme.

The theme for the campaign is ‘Road Safety-Teach the Child now!’

Source: Ghana News Agency

Nkwanta Yam Sellers appeal for sheds, toilet facility

Mr Philip Osei, the Secretary of Nkwanta Yam Sellers Association, has complained about the lack of market sheds saying it is a major challenge preventing effective trading of its members.

Mr Osei speaking to the Ghana News Agency (GNA) said all efforts to reach the authorities, especially the Municipal Assembly, had yielded no results.

He said the failure on the part of authorities to urgently address the challenges continued to affect their daily activities, adding that trading in the open without a roof over their heads exposed them to the rains and scorching sun.

Mr Osei said sometimes tubers of yam that were unsold get rotten due to the excessive heat from the direct sunlight.

Some farmers corroborated the concerns raised by Mr Osei, saying the increased prices of new yam could be attributed to the hike in price of farming inputs.

They urged the government to ensure the supply farming inputs to help reduce the price of food stuff in the market.

Some concerns also bother on the bad roads leading to their various farms and how transport of yam to the market was also affected.

Madam Victoria Lelewu, the Market Queen also appealed for a toilet facility at the market to ease the stress that traders often go through when ‘nature calls.’

She said open defecation had become the order of the day due to the absence of toilets for traders at the market.

Madam Lelewu said they hoped the Assembly would, as a matter of urgency, consider their plights and provide possible solutions for them.

Source: Ghana News Agency

Abutia SHS: All 23 students discharged from hospital after suspected food poisoning

All 23 students of the Abutia Senior High School (ABUSCO), who suffered food poisoning after they ate a rice meal on campus last Wednesday, have been discharged from hospital.

Mr Claude Dziseaku, the Physician Assistant of the Mater Ecclesiae Hospital at Sokode, in the Ho Municipality told the Ghana News Agency, the students were rushed to the facility with abdominal pains, vomiting and diarrhoea on Friday night, but had since been treated and discharged.

He said the Public Health Unit of the hospital had started investigations into the case.

Mr Leonard Nyatsoe, the Headmaster of the School, in an interview with the Ghana News Agency, said the affected students had regained their strength.

He said the Ghana Education Service, the Ghana Health Service and the Police had opened a fact-finding investigation into the incident to guide stakeholders against future occurrence.

Students of ABUSCO, who consumed fried rice on campus on Wednesday and Thursday, suffered abdominal pains, vomiting and diarrhoea, and were rushed to the Mater Eclessiae Hospital, where they were admitted and stabilised.

He said the situation was chaotic as some of the students were paired on a bed due to the nature of the cases and the numbers involved.

Mr Nyatsoe said about 10 staff, who were off duty, were called to assist them in the situation and by 1500 hours on Saturday, nine of the students were discharged after their situation improved.

Source: Ghana News Agency